Hyo-Soo Kim, MD, PhD.

 

Research Topics

 

Clinical Research : cardiovascular intervention (antiplatelet therapy, CTO, TAVI)

 

 

Basic Research : stem cell biology (iPS, fate conversion, MSC, cardiac stem cell) & cell therapy

 

 

Publications : he has published over 200 papers in SCI-journals as the first or corresponding author, including Lancet, Cell Metabolism, Circulation, JACC, European Heart J, EBMO J, Blood, Circulation Research, J Cell Research, FASEB J., ATVB, Stem Cells, Molecular Med, Molecular Therapy, JBC, Can Med Assoc J.

 

EDUCATION

Mar. 1978 - Feb. 1980      Premedical Course, College of Liberal Arts & Science,

                                                Seoul National University

Mar. 1980 - Feb. 1984      Seoul National University College of Medicine

( M.D. )

Mar. 1985 - Feb. 1987      Postgraduate School, Seoul National University

                                                ( Master of Medical Science )

Mar. 1987 - Aug. 1994     Postgraduate School, Seoul National University

                                                ( Ph.D. in Medical Science )

 

BRIEF CHRONOLOGY of EMPLOYMENT

Mar. 1984 - Feb. 1985      Internship,

                                                Seoul National University Hospital, Seoul, Korea

Mar. 1985 - Feb. 1988      Residency in Internal Medicine,

                                                Seoul National University Hospital, Seoul, Korea

Mar. 1988 - Apr. 1991      Military Medical Officer, Captain,

                                                Department of Internal Medicine,

                                                Seoul District Army General Hospital, Seoul, Korea

May. 1991 - Aug. 1992     Clinical Fellowship in Cardiology,

                                                Seoul National University Hospital, Seoul, Korea

Sep. 1992 - Feb. 1994      Visiting Researcher in Molecular Cardiology,

                                                3rd Department of Internal Medicine,

                                                Faculty of Medicine, University of Tokyo, Tokyo, Japan

Mar. 1994  - Feb. 1996     Instructor, Division of Cardiology,

                                                Department of Internal Medicine,

                                                Seoul National University Hospital

Mar. 1996  - Feb. 2000     Assistant Professor, Division of Cardiology,

                                                Department of Internal Medicine,

                                                Seoul National University Hospital

Jan. 2000 – Jan. 2002      Visiting scholar, Division of Cardiovascular Research,

                                                St. Elizabeth Medical Center, Boston, MA, USA

Mar. 2000 – Mar. 2006     Associate Professor, Division of Cardiology,

Department of Internal Medicine / Cardiovascular Center

                                                Seoul National University Hospital

Apr. 2006 – present         

• Professor, Department of Internal Medicine, Seoul National University College of Medicine

l  Chairman & Chief, Cardiovascular Center, Seoul National University Hospital

l  Director of National Research Laboratory for Cardiovascular Stem Cell Niche, Seoul National University.

l  Fellow, American Heart Association [미국 심장학회 정회원]

l  대한민국 한림원 종신 정회원

l  대한민국 한림의학원 정회원

l  Chairman, Board of Directors, Korean Society of Interventional Cardiology (since April 2016)

 

RESEARCH INTERESTS

“stem cell biology & its application”

 

AWARADS

 

1. 2006. 11. 국가연구개발 우수성과 100선 선정 (과학기술부)

Award of Top 100 Excellent R & D project sponsored by Ministry of Science & Technology, Korea

2. 2006. 12.14 보건복지부 우수연구자 (보건복지부)

Award of Excellent Scientist (Ministry of Health & Welfare, Korea)

3. 2007.05.16. 2006년도 SCI Impact Factor 상 1위 (서울대학교병원/서울대학교 의과대학)

The premier prize based on SCI impact factors of papers in 2007 among faculties in Seoul National University College of Medicine

4. 2008.03.21 제1회 아산의학상 (아산사회복지재단)

The First Asan Medical Award (prize money = US $ 200,000)

5. 2008.04.08. 우수연구상 (서울대학교)

Award for Excellent Scientist in Seoul National University

6. 2008.05.15 제 1회 지석영상 (서울대학교 의과대학)

The premier prize based on SCI impact factors of papers in 2008 among faculties in Seoul National University College of Medicine

7, 2009. 05.15 제 2회 지석영상 (서울대학교 의과대학)

The premier prize based on SCI impact factors of papers in 2009 among faculties in Seoul National University College of Medicine

8. 2009.11.04. 2009 한국연구재단 대표우수성과 (교육과학기술부/한국연구재단)

Award of Top 100 Excellent R & D project sponsored by Ministry of Science & Technology, Korea

9. 2010.11.15 제 3회 지석영상 (서울대학교 의과대학)

The premier prize based on SCI impact factors of papers in 2010 among faculties in Seoul National University College of Medicine

10. 2011.5.15 제 4회 지석영상 (서울대학교 의과대학)

The premier prize based on SCI impact factors of papers in 2011 among faculties in Seoul National University College of Medicine

11. 2014.5 서울의대 연구실적 제 1위상 (서울대학교 의과대학)

The premier prize based on SCI impact factors of papers in 2014 among faculties in Seoul National University College of Medicine

12. 2014.11 제 24회 분쉬의학상 본상 (대한의학회)

The 24th Wunsch medical award

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PATENTS

 

1. 인간줄기세포에서 고활성 줄기세포를 분리하는 방법 및 상기 방법에 의해 분리된 고활성 줄기세포 (한국특허출원 제2008-73383호 / PCT 국제출원 PCT/KR2009/003954)

The innovative method to isolate highly-active stem cells from human stem cells

2. 성체세포로부터 만능줄기세포를 유도하는 방법 및 그 방법에 의해 제조된 만능줄기세포 (출원번호 ; 10-2009-0089330 )

The innovative method to produce the induced pluripotent stem cells from adult mature cells

3. VE-카드헤린 항체가 코팅된 스텐트 (출원 번호: 10-2009-0088608)

Pro-healing bio-coronary stent coated with antibody for VE-cadherin

4. 인간 지방줄기세포의 고활성을 유도하는 방법 및 배지 (출원진행중)

The innovative culture method to produce the highly-active cells from human adipose tissue-derived stem cells

5. 배아줄기세포의 추출물을 이용한 맞춤형 만능줄기세포의 유도 방법 및 상기 방법에 의해 제조된 만능줄기세포 (출원 번호:10-2008-0056282)

The innovative method to produce iPS cells by treatment of mature cells with lysate of embryonic stem cells.

 

CLINICAL TRIAL EXPERIENCE

RECOVER, PROMISS, NASPI TRIALS ;

1.renal toxicity after coronary angiography [PI]

2. MAGIC CELL TRIAL 1,2,3-DES ; cell therapy for patient with MI [PI]

3. COREA TRIAL ; celecoxib for late loss at stented segment after PCI [PI]

4. CILON-T TRIAL ; cilostazol & statin for cardiovascular events after PCI [PI]

5. ROMEO TRIAL ; rosuvastatin for dyslipidemia in patients with metabolic syndrome [PI]

6. CRESTOR KOREA LAUNCH TRIAL [PI]

7. TORCETRAPIB MULTINATIONAL STUDY

8. OMACOR KOREA MULTICENTER STUDY [PI]

9. EXLIP KOREA MULTICENTER STUDY [PI]

10. OASIS 5 & 6 MULTINATIONAL STUDY

11. APPROACH MULTINATIONAL STUDY (GSK)

12. SEPIA MULTINATIONAL STUDY

13. AMODIPINE KOREA MULTICENTER STUDY [PI]

14. KoPre-CAD/DM KOREA MULTICENTER STUDY [PI]

15. EXCELLENT KOREA MULTICENTER STUDY [PI]

16. ECO-PLEASANT KOREA MULTICENTER STUDY [PI]

17. Korea Lipilow Multicenter study [PI] [KOLIPIOLOW]

18. Korea Lipinon Multicenter study [PI] [KOLIPINON]

19. STABILITY MULTINATIONAL STUDY [PI] (GSK)

20. Prasugrel MULTINATIONAL STUDY [Lilly]

21. TACE MULTINATIONAL STUDY [Lilly]

22. LIFENOX MULTINATIONAL STUDY [Sanofi-Aventis]

23. ENGAGE-AF MULTINATIONAL STUDY [Sankyo]

24. IMPROVE-IT MULTINATIONAL STUDY [MSD]

25.EINSTEIN MULTINATIONAL STUDY [PI] (BAYER)

26.TRACER MULTINATIONAL STUDY [PI] (SCHERING-PLOUGH)

 

CERTIFICATES

• Korea Board of Medical Doctor ; 27492

• Korea Board of Internal Medicine ; 2592

• Korea Board of Cardiology Subspecialty ; 2-97-234